Nmr Shielding And Deshielding Pdf Download, advocacy coalition framework pdf download
c5cfac679b Send to Blogs and Networks Processing . Applied Magnetic Strength is called as NMR Spectrum. Slide 14:14 The spectrum is measured on a delta (d) scale in units of parts per million (ppm) Lower frequency is to the left in the spectrum; these absorptions are said to be downfield Higher frequency is to the right in the spectrum: these absorptions are said to be upfield The small signal at d 0 corresponds to an internal standard called tetramethylsilane (TMS) used to calibrate the chemical shift scale The number of signals in the spectrum corresponds to the number of unique sets of protons CHEMICAL SHIFT () :CHEMICAL SHIFT () * The variations of nuclear magnetic resonance frequencies of the same kind of nucleus, due to variations in the electron distribution Chemical Shift = Absorption Frequency relative to TMS (Hz) Spectrometer Frequency (MHz) Slide 16:*Key to the utility of NMR in chemistry Different 1H in different molecules exhibit different absorption frequencies *Arise from the electron cloud effects of nearby atoms or bonds, which act as little magnets to shift absorption n up or down *Mostly affected by electronegativity of neighbouring atoms or groups Tetra methylsilane (TMS) :Tetra methylsilane (TMS) Only one peak on NMR spectrum High electronic density of H in TMS. RAVISHANKAR * By - MOHAMMED IRFAAN :* By - MOHAMMED IRFAAN View More Presentations Computer Viruses And Its Effects By: csumityadav Create a spotlight effect in powerpoint By: authorSTREAM Difference between animation effects and transition effects By: PowerPointinfo shielding & deshielding effct - by irfaan By: irfaanshaik Inflation and its effect By: smilemahesh Adobe After Effects By: cameronhogwood8 EFFECTS OF SMOKING By: aSGuest31316 Environmental Effects Of Landfill By: maniyahoo plastics and its effects on environment By: sk900 HALL EFFECT SENSOR By: Lavuammu Tags Nmr spectroscopy *You can't enter more than 5 tags. In order to view it, please contact the author of the presentation. UpdateClose Presentation Statistics loading. etc.) * Cholesterol and lipoprotein testing * Chemical Shift Imaging (MRI MRS) *Pharmaceutical Biotechnology (proteins, protein drugs, SAR by NMR REFERENCE :REFERENCE WEBSITES www.wikipedia.com BOOKS PHARMACEUTICAL ANALYSIS VOL II BY DR A.V KASTURE , DR S.G WADODKAR INSTANT NOTES IN ANALYTICAL CHEMISTRY BY D .KEALEY PHARMACEUTICAL ANALYSIS BY R.S . Comments Posting comment. All rights reserved. logging in or signing up shielding& deshielding effect by irfaan irfaanshaik Download Post to : URL : Related Presentations : Let's Connect Share Add to Flag Embed Email Add to Channel Copy embed code: Embed: Flash iPad Dynamic Copy Does not support media & animations Automatically changes to Flash or non-Flash embed WordPress Embed Customize Embed Use HTTPS URL: Copy Thumbnail: Copy The presentation is successfully added In Your Favorites.
CHARACTERISTIC CHEMICAL SHIFTS :CHARACTERISTIC CHEMICAL SHIFTS Slide 19:Shielding and Deshielding of Protons SHIELDING EFFECT Protons in an external magnetic field absorb at different frequencies depending on the electron density around that proton High electron density around a nucleus shields the nucleus from the external magnetic field Shielding causes absorption of energy at higher frequencies (more energy is required for this nucleus to flip between spin states) - the signals are upfield in the NMR spectrum DESHIELDING EFFECT :DESHIELDING EFFECT Lower electron density around a nucleus deshields the nucleus from the external magnetic field * Deshielding causes absorption of energy at lower frequencies (less energy is required for this nucleus to flip between spin states) the signals are downfield in the NMR spectrum Shielding & Deshielding Scale :Shielding & Deshielding Scale FACTORS INFLUENCING CHEMICAL SHIFT :FACTORS INFLUENCING CHEMICAL SHIFT Both 1H and 13C Chemical shifts are related to the following major factors: Depends on Hydrogen bonding Depends on adjacent group Depends on carbon group attached Depends on hybridization Depends on anisotropy APPLICATIONS :APPLICATIONS *Analysis of blood, urine and other biofluid mixtures to quantify and identify metabolite changes *Allows one to detect drug toxicity and even localize toxicity (for preclinical trials) in a non-invasive way *Detection, identification and quantitation of primary and secondary drug metabolites Other Applications :Other Applications * Clinical testing (detection of inborn errors of metabolism, cancer, diabetes, organic solvent poisoning, drugs of abuse, etc. Channel Statistics Included in these Channels: You do not have the permission to view this presentation. Go Premium Sign Up Sign In Take a Tour Help Home Browse Browse Presentations Featured Presentations Most Viewed Channels Categories Greeting Cards PowerPoint Templates PowerPoint Templates PowerPoint Diagrams Upload Upload from Desktop Single File Upload Presentations (PPT, KEY, PDF) Presentations (PPT, KEY, PDF) PowerPoint Templates . Measures the absorption of EM radiation in the radiofrequency region 4 MHz to 750 MHz (wavelength 0.4 m to 75 m) Most commonly done on 1H and 13C. Numeric tags are not allowed. Account Join Now Sign In Premium My Presentations Education Specials RSS Featured Featured Audio Featured Animated Latest Uploads Most Liked Most Viewed Featured Lessons Browse Podcast Featured Featured Audio Featured Animated Latest Uploads Most Liked Most Viewed Categories Facebook App Developers Get your Widget Channels Latest Members PowerPointTemplatesNEW Help & Info About Us Help API FAQ Contact Us Terms and Conditions Privacy Policy Blog Forum What's new? Careers Webinars Why authorSTREAM Feature Tour How it Works PowerPoint to Video & iPod PowerPoint on Blogs PowerPoint to Flash Share Presentations Online Present Live Presentations on iPad Presentation Analytics Branded Channels Video in PPT Greeting Cards Referral authorSTREAM Desktop Buzz on authorSTREAM Follow us on: Go to Application Have a question? Call us at US 210-787-1860 Open Monday to Friday, 8 AM to 6 PM EST 2014 authorSTREAM. Premium member Presentation Transcript * SHIELDING &DESHIELDInG EFFECT * :* SHIELDING &DESHIELDInG EFFECT * By Mohammed Irfaan 07T61R0049 VI th Year , B.pharmacy Azad College Of Pharmacy PHARMCEUTICAL ANALYSIS OUTLINE OF PRESENTATION :OUTLINE OF PRESENTATION Introduction Of NMR Spectroscopy Chemical shift Shielding And Deshielding Effect Factors influencing chemical shift Nmr spectroscopy :Nmr spectroscopy * Nuclear Magnetic Resonance Spectroscopy * NMR Spectroscopy - Intro :NMR Spectroscopy - Intro The study of spin changes at the nuclear level when radio frequency energy is absorbed in the presence of magnetic field.
Bernebiha replied
478 weeks ago